The STATs on Naive iPSC Reprogramming
نویسندگان
چکیده
منابع مشابه
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Global DNA demethylation is an integral part of reprogramming processes in vivo and in vitro, but whether it occurs in the derivation of induced pluripotent stem cells (iPSCs) is not known. Here, we show that iPSC reprogramming involves both global and targeted demethylation, which are separable mechanistically and by their biological outcomes. Cells at intermediate-late stages of reprogramming...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2010
ISSN: 1934-5909
DOI: 10.1016/j.stem.2010.08.005